Background Patients with medically unspecified disease (MUD) may present at any disease stage, with clinical manifestations and test results that do not lead to a clear diagnosis, posing a common challenge in clinical settings. General practitioners, with their patient-centered approach and holistic medical models, have an advantage in diagnosing and treating MUD. Standardizing the diagnosis and treatment of MUD is a crucial skill for general practitioners. However, there is currently a lack of data on the treatment of MUD in general outpatient clinics of comprehensive tertiary hospitals. Objective This study examines the prevalence of medically unexplained symptoms (MUS) in general outpatient clinics, offering insights for general practitioners in tertiary hospitals on diagnosing and treating MUS. It also serves as a foundation for standardizing the diagnostic and treatment protocols for MUD. Methods Select patients diagnosed with medically unspecified disease (MUD) who visited the outpatient department of our general medicine department between September 2021 and September 2022. Collect basic information and follow-up data for one year post-visit, and analyze the reasons for the initial visit and subsequent follow-up outcomes. Results A total of 576 patients with MUD received treatment at the general outpatient department, with an average age of (44.97 ± 13.50) years. There was no statistically significant difference in the age distribution among male and female MUD patients (P > 0.05). Chest pain was the most common reason for treatment of medically unspecified disease in the general outpatient department. Among patients treated for chest pain, there were more males than females (P < 0.05), and a greater number of patients were treated in specialized clinics compared to general clinics (P < 0.05), The majority of patients remained undiagnosed and had either 0 or no more than 2 visits within a year. There was no significant correlation between anxiety scores and age, although female patients, those with chest pain, healthcare staff, and non-smokers reported higher levels of self-anxiety. Conclusion MUD patients have various reasons for seeking medical treatment. General practitioners in comprehensive tertiary hospitals should make full use of relevant resources, attach importance to the full evaluation of the psychological status of MUD patients, standardize the diagnosis and treatment process of MUD, and provide more comprehensive diagnosis and treatment services.
Published in | American Journal of Clinical and Experimental Medicine (Volume 12, Issue 4) |
DOI | 10.11648/j.ajcem.20241204.11 |
Page(s) | 45-51 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Medically Unspecified Disease, Comprehensive Tertiary Hospitals, General Practice, Medical Treatment, Anxiety Score
[1] | Van Dessel, N., Leone, S. S., van der Wouden, J. C., Dekker, J., & van der Horst, H. E. 2014. The PROSPECTS study: design of a prospective cohort study on prognosis and perpetuating factors of medically unexplained physical symptoms (MUPS). Journal of psychosomatic research 76: 200–206. |
[2] | Gol, J., Terpstra, T., Lucassen, P., Houwen, J., van Dulmen, S., Olde Hartman, T. C., & Rosmalen, J. 2019. Symptom management for medically unexplained symptoms in primary care: a qualitative study. The British journal of general practice: the journal of the Royal College of General Practitioners 69: e254–e261. |
[3] | Zhou YF, Fang LZ, Yu DH, Ma L, Wang LY & Feng M. 2021. The orientation and development strategy of general medicine in general hospital [J]. Chinese General Medicine 13: 1581-1584+1591. |
[4] | Pan Q, Ren JJ, Zhang M, Yin ZX, He Q, Yao CJ & Wang Z. 2023. How does undifferentiated disease resonate with general practice at the same frequency? [J]. Chinese General Medicine 31: 3877-3883. |
[5] | Hilderink, P. H., Collard, R., Rosmalen, J. G., & Oude Voshaar, R. C. 2013. Prevalence of somatoform disorders and medically unexplained symptoms in old age populations in comparison with younger age groups: a systematic review. Ageing research reviews 12: 151–156. |
[6] | Baitha, U., Deb, K. S., Ranjan, P., Mukherjee, A., Bauddh, N. K., Kaloiya, G. S., Kumar, A., & Jadon, R. S. 2019. Estimated prevalence of medically unexplained physical symptoms in the medicine outpatient department of a tertiary care hospital in India. General hospital psychiatry 61: 47–52. |
[7] | Pu, J., & Zhang, J. 2018. Study on the influencing factors of depression and anxiety in elderly patients with chronic diseases [J]. Journal of Community Medicine 16: 1701-1704. |
[8] | Zhou ZH, Huang WJ, Chen SY, Guo JZ & Jin SH. 2012. Study on the causes and diagnosis of general practice outpatients in tertiary general hospital [J]. Chinese General Medicine 23: 2652-2655. |
[9] | Probst, J. C., Moore, C. G., Baxley, E. G., & Lammie, J. J. 2002. Rural-urban differences in visits to primary care physicians. Family medicine 34: 609–615. |
[10] | Svansdottir, E., Hreggvidsdottir, S., Sigurdardottir, B., Benedikz, E., Andersen, K., & Karlsson, H. D. 2018. Non-cardiac chest pain and its association with persistent chest pain and poor mental well-being. Laeknabladid 104: 71–77. |
[11] | De Wolff, J. F., & Fawcett, K. M. 2019. Non-Cardiac Chest Pain. Acute medicine 18: 260. |
[12] | Wang RY, Li F, Zhi X, He ZY, Wang Y, Zhao WW & Zhang M. 2016. Orientation and development of general practice department of general hospital in hierarchical diagnosis and treatment based on disease spectrum of outpatients [J]. Chinese General Practice 19: 3417-3421. |
[13] | Qu S, Shi XX, Xie ZJ, Ding RJ, & Zheng MJ. 2021. Validity and reliability of patient health questionnaire and generalized anxiety disorder scale for screening depression and anxiety in non-cardiac chest pain patients. Chinese Journal of Mental Health 35: 376, 381. |
[14] | Zhao WW, Wang RY, Zhang JJ, Wang YY, Zhang YL & Sun YJ. 2019. Comparative study on visit status of patients with medically unexplained physical symptoms from general practice ward and specialist ward in general hospitals. [J]. Chinese General Practice 22: 20-23. |
[15] | Liu GQ, Chen ZG. 1997. Survey of smoking cessation anxiety and discussion of countermeasures. [J]. Journal of North Sichuan Medical College 1997: 62-63. |
APA Style
Xu, S., Liu, J., Chen, Y., Zhang, Q. (2024). Analysis of Medically Unspecified Disease in the General Outpatient Department of a Comprehensive Tertiary Hospital. American Journal of Clinical and Experimental Medicine, 12(4), 45-51. https://doi.org/10.11648/j.ajcem.20241204.11
ACS Style
Xu, S.; Liu, J.; Chen, Y.; Zhang, Q. Analysis of Medically Unspecified Disease in the General Outpatient Department of a Comprehensive Tertiary Hospital. Am. J. Clin. Exp. Med. 2024, 12(4), 45-51. doi: 10.11648/j.ajcem.20241204.11
@article{10.11648/j.ajcem.20241204.11, author = {Shuang Xu and Jing Liu and Yun Chen and Qing Zhang}, title = {Analysis of Medically Unspecified Disease in the General Outpatient Department of a Comprehensive Tertiary Hospital }, journal = {American Journal of Clinical and Experimental Medicine}, volume = {12}, number = {4}, pages = {45-51}, doi = {10.11648/j.ajcem.20241204.11}, url = {https://doi.org/10.11648/j.ajcem.20241204.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20241204.11}, abstract = {Background Patients with medically unspecified disease (MUD) may present at any disease stage, with clinical manifestations and test results that do not lead to a clear diagnosis, posing a common challenge in clinical settings. General practitioners, with their patient-centered approach and holistic medical models, have an advantage in diagnosing and treating MUD. Standardizing the diagnosis and treatment of MUD is a crucial skill for general practitioners. However, there is currently a lack of data on the treatment of MUD in general outpatient clinics of comprehensive tertiary hospitals. Objective This study examines the prevalence of medically unexplained symptoms (MUS) in general outpatient clinics, offering insights for general practitioners in tertiary hospitals on diagnosing and treating MUS. It also serves as a foundation for standardizing the diagnostic and treatment protocols for MUD. Methods Select patients diagnosed with medically unspecified disease (MUD) who visited the outpatient department of our general medicine department between September 2021 and September 2022. Collect basic information and follow-up data for one year post-visit, and analyze the reasons for the initial visit and subsequent follow-up outcomes. Results A total of 576 patients with MUD received treatment at the general outpatient department, with an average age of (44.97 ± 13.50) years. There was no statistically significant difference in the age distribution among male and female MUD patients (P > 0.05). Chest pain was the most common reason for treatment of medically unspecified disease in the general outpatient department. Among patients treated for chest pain, there were more males than females (P < 0.05), and a greater number of patients were treated in specialized clinics compared to general clinics (P < 0.05), The majority of patients remained undiagnosed and had either 0 or no more than 2 visits within a year. There was no significant correlation between anxiety scores and age, although female patients, those with chest pain, healthcare staff, and non-smokers reported higher levels of self-anxiety. Conclusion MUD patients have various reasons for seeking medical treatment. General practitioners in comprehensive tertiary hospitals should make full use of relevant resources, attach importance to the full evaluation of the psychological status of MUD patients, standardize the diagnosis and treatment process of MUD, and provide more comprehensive diagnosis and treatment services. }, year = {2024} }
TY - JOUR T1 - Analysis of Medically Unspecified Disease in the General Outpatient Department of a Comprehensive Tertiary Hospital AU - Shuang Xu AU - Jing Liu AU - Yun Chen AU - Qing Zhang Y1 - 2024/10/31 PY - 2024 N1 - https://doi.org/10.11648/j.ajcem.20241204.11 DO - 10.11648/j.ajcem.20241204.11 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 45 EP - 51 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/j.ajcem.20241204.11 AB - Background Patients with medically unspecified disease (MUD) may present at any disease stage, with clinical manifestations and test results that do not lead to a clear diagnosis, posing a common challenge in clinical settings. General practitioners, with their patient-centered approach and holistic medical models, have an advantage in diagnosing and treating MUD. Standardizing the diagnosis and treatment of MUD is a crucial skill for general practitioners. However, there is currently a lack of data on the treatment of MUD in general outpatient clinics of comprehensive tertiary hospitals. Objective This study examines the prevalence of medically unexplained symptoms (MUS) in general outpatient clinics, offering insights for general practitioners in tertiary hospitals on diagnosing and treating MUS. It also serves as a foundation for standardizing the diagnostic and treatment protocols for MUD. Methods Select patients diagnosed with medically unspecified disease (MUD) who visited the outpatient department of our general medicine department between September 2021 and September 2022. Collect basic information and follow-up data for one year post-visit, and analyze the reasons for the initial visit and subsequent follow-up outcomes. Results A total of 576 patients with MUD received treatment at the general outpatient department, with an average age of (44.97 ± 13.50) years. There was no statistically significant difference in the age distribution among male and female MUD patients (P > 0.05). Chest pain was the most common reason for treatment of medically unspecified disease in the general outpatient department. Among patients treated for chest pain, there were more males than females (P < 0.05), and a greater number of patients were treated in specialized clinics compared to general clinics (P < 0.05), The majority of patients remained undiagnosed and had either 0 or no more than 2 visits within a year. There was no significant correlation between anxiety scores and age, although female patients, those with chest pain, healthcare staff, and non-smokers reported higher levels of self-anxiety. Conclusion MUD patients have various reasons for seeking medical treatment. General practitioners in comprehensive tertiary hospitals should make full use of relevant resources, attach importance to the full evaluation of the psychological status of MUD patients, standardize the diagnosis and treatment process of MUD, and provide more comprehensive diagnosis and treatment services. VL - 12 IS - 4 ER -