Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire

Sekongo Yassongui Mamadou; Kouamenan Goore Sidonie; Kassogue Kadidia; Konan Sidoine; Kouassi Parfait; Lagou Amélie Delphine; Kouacou-Ama Patricia; Konate Seidou; Abisse Agba

doi:doi:10.11648/j.iji.20150304.11

Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire

Sekongo Yassongui Mamadou, Kouamenan Goore Sidonie, Kassogue Kadidia, Konan Sidoine, Kouassi Parfait, Lagou Amélie Delphine, Kouacou-Ama Patricia, Konate Seidou, Abisse Agba

Published in International Journal of Immunology (Volume 3, Issue 4)

Received: 17 June 2015 Accepted: 22 June 2015 Published: 4 July 2015

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

The objective of this study is to establish the mapping of blood group and phenotype Rhesus and Kell and compare it to the population of blood donors. Methodology: It is a prospective study performed in transfusion therapy unit (UTT) of the national blood transfusion center (NBTC) of Abidjan on sickle cell desease patients multitransfused between February and October 2013. The blood group ABO and phenotype Rhesus and Kell of the patients was performed by the gel agglutination technique. The statistical analysis was performed using SPSS 15.0 software. Results: Among the 145 patients followed by the UTT, males predominated with (sex ratio 1.27). The median age was 14 years. Homozygous sickle cell disease (SS) was more frequent (57.25%). The blood group O was more represented (54.6%). Ag D was found in 96%. The Ag C (16.5%) and Ag E (14.5%) have lower frequencies than those founded in the population of blood donors (Ag C 21.6% and Ag E 22.2%). The most phenotype rhesus and kell frequently encountered to the patients was C- c+ E- e+ K- (49.7%). These frequencies are lower than those of the blood donors population. Conclusion: Blood group O is the most common to our patients. The Ag D is the most found. The phenotype Rhesus and kell C- c + D + E- e- K- predominates with but remains below the frequencies reported among blood donors. This proves that there are risks of alloimmunization to these patients; hence the necessity to transfuse according to the protocol phenotyped and compatibility.

Published in	International Journal of Immunology (Volume 3, Issue 4)
DOI	10.11648/j.iji.20150304.11
Page(s)	47-51
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Mapping, Blood Group and Phenotyps Rhesus and Kell, Sickle Cell Desease Patients, Transfusion Program

References

[1]	Marion E. Reid et Christine Lomas-Francis, The blood group antigen, Facts Book, Elsevier Academic Press, 2° édition, 2004.
[2]	Marion E. Reid et Christine Lomas-Francis, The blood group antigen & antbodies, SBB Books New Yrok, 2007
[3]	Dembele B., Otchoumou K., Siransy B.L., Sekongo Y.M., Abissey A.S. Etude de la compatibilité érythrocytaire Rhesus Kell entre donneur de sang et receveurs à Abidjan. Rev. Int. Sc. Méd. 2009,11 ; 3 : 21-25.
[4]	Sangaré A. La douleur drépanocytaire. J Panafr Douleur 1995 : 1-12.
[5]	A.Tolo-Diebkile Drépanocytose homozygote chez l’adulte ivoirien de plus de 21 ans, John Libbey Eurotext. 2010, 20 ; 2 : 63-67
[6]	Eloundou C.O. Prise en charge de la crise douloureuse drépanocytaire selon les critères de L’OMS. Une étude en milieu hospitalier pédiatrique à Libreville. Thèse méd. Bamako : 02-M-32
[7]	Diallo D. Suivi des enfants drépanocytaires de 0-15 ans dans le service de pédiatrie du CHU GT. Thèse méd. Bamako : 04-M-16
[8]	Neonatomg Etude descriptive dans 4 centres Parisiens chez 299 patients suivi de 1987-1997. Eur J Haematol 2000
[9]	Cabannes R., Sendrail A., Pene F., Sangare A., Sombo M. E., Kple F. P. Etude de l'hémotypologie des populations d'Afrique de l'Ouest. Ann. Univ. Abidjan, 1979,13 ; B : 105-135.
[10]	Siransy Bogui L., Dembele B., Sekongo Y., Abisse S., Konaté S., and Sombo M. Phenotypic Profile of Rh and Kell Blood Group Systems among Blood Donors in Cote d’Ivoire, West Africa. Hindawi Publishing Corporation Journal of Blood Transfusion 2014, ID 309817 : 4 p
[11]	Dulat C., Rey J.L., Trolet C. Répartition ethnique des groupes sanguins en Côte d’Ivoire Méd. D’Afr. Nr. 1989, 36 (11)
[12]	Rapport d’activité du centre national de transfusion sanguine de côte d’ivoire 2010
[13]	Rapport d’activité du centre national de transfusion sanguine de côte d’ivoire 2011
[14]	Rapport d’activité du centre national de transfusion sanguine de côte d’ivoire 2012
[15]	Corrain C. Et Capitanio M.Quelques observations hémotypologiques à propos des Dida (Côte d’Ivoire) Bulletins et Mémoires de la Société d’anthropologie de Paris, 1984, 1 : 83-90
[16]	Falusi AG, Ademowo OG, Latunji CA, Okeke AC, Olatunji PO, Onyekwere TO, Jimmy EO, Raji Y, Hedi CC, Otukonyong EE, Itata EO. “Distribution of ABO and RH genes in Nigeria,” African Journal of Medicineand Medical Sciences 2000, 29 ;1 : 23–26.
[17]	Chiaroni J., Roubinet F., Bailly P., Mannessier L., Noizat-pirennef. Les analyses immunohématologiques et leurs applications cliniques, Edit : John Libbey Eurotext. 2
[18]	Daniels G., Human Blood Group, John Willey & Sons, Hoboken, NJ, USA, 2nd edition, 2002.
[19]	Wagner F.F., Kasulke D., Kerowgan M., and Flegel W.A. “Frequencies of the blood groups ABO, Rhesus, D category VI, Kell, and of clinical relevant high-frequency antigens in southwestern Germany,” Infusions therapie und Transfusions medizin 1995, 22 ; 5 : 285–290.
[20]	Akre DP, Seka-Seka J, Dasse SR, Kple-Faget P, Hien S, N’Guessan K, Sombo MF. “Alloimmunisation anti ´erythrocytaire post transfusionnelle chez les drépanocytaires au CHU de Cocody Abidjan,” International Journal of Pharma and Bio Sciences 2008, 9 ; 2 : 64–70.
[21]	Vichensky EP, Luban N, Wright E, Olivieri N. Prospective RBC phenotype matching in a stroke-preven¬tion trial in sickle cell anemia: a multicenter transfusion trial. Transfusion. 2001;41:1086–1092.
[22]	Murao M et Viana MB. Risk factors for alloimmunization by patients with sickle- cell disease. Braz J Med Biol Res. 2005, 38 ; 5: 675-82.
[23]	Norol F, Nadjahi J, Bachir D et al. Transfusion and alloimmunization in sickle-cell anemia patients. Transfus Clin Biol.; 1994, 1 ; 1: 27-34.
[24]	Orilina AR, Ungerp J et M Koshy () Post transfusion alloimmunisation in patients with Sickle-cell anemia. Amer. J Hematol. 1978, 5 ; 1: 101-6.

Cite This Article

Plain Text BibTeX RIS

APA Style

Sekongo Yassongui Mamadou, Kouamenan Goore Sidonie, Kassogue Kadidia, Konan Sidoine, Kouassi Parfait, et al. (2015). Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire. International Journal of Immunology, 3(4), 47-51. https://doi.org/10.11648/j.iji.20150304.11

Copy | Download

ACS Style

Sekongo Yassongui Mamadou; Kouamenan Goore Sidonie; Kassogue Kadidia; Konan Sidoine; Kouassi Parfait, et al. Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire. Int. J. Immunol. 2015, 3(4), 47-51. doi: 10.11648/j.iji.20150304.11

Copy | Download

AMA Style

Sekongo Yassongui Mamadou, Kouamenan Goore Sidonie, Kassogue Kadidia, Konan Sidoine, Kouassi Parfait, et al. Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire. Int J Immunol. 2015;3(4):47-51. doi: 10.11648/j.iji.20150304.11

Copy | Download

@article{10.11648/j.iji.20150304.11,
  author = {Sekongo Yassongui Mamadou and Kouamenan Goore Sidonie and Kassogue Kadidia and Konan Sidoine and Kouassi Parfait and Lagou Amélie Delphine and Kouacou-Ama Patricia and Konate Seidou and Abisse Agba},
  title = {Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire},
  journal = {International Journal of Immunology},
  volume = {3},
  number = {4},
  pages = {47-51},
  doi = {10.11648/j.iji.20150304.11},
  url = {https://doi.org/10.11648/j.iji.20150304.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150304.11},
  abstract = {The objective of this study is to establish the mapping of blood group and phenotype Rhesus and Kell and compare it to the population of blood donors. Methodology: It is a prospective study performed in transfusion therapy unit (UTT) of the national blood transfusion center (NBTC) of Abidjan on sickle cell desease patients multitransfused between February and October 2013. The blood group ABO and phenotype Rhesus and Kell of the patients was performed by the gel agglutination technique. The statistical analysis was performed using SPSS 15.0 software. Results: Among the 145 patients followed by the UTT, males predominated with (sex ratio 1.27). The median age was 14 years. Homozygous sickle cell disease (SS) was more frequent (57.25%). The blood group O was more represented (54.6%). Ag D was found in 96%. The Ag C (16.5%) and Ag E (14.5%) have lower frequencies than those founded in the population of blood donors (Ag C 21.6% and Ag E 22.2%). The most phenotype rhesus and kell frequently encountered to the patients was C- c+ E- e+ K- (49.7%). These frequencies are lower than those of the blood donors population. Conclusion: Blood group O is the most common to our patients. The Ag D is the most found. The phenotype Rhesus and kell C- c + D + E- e- K- predominates with but remains below the frequencies reported among blood donors. This proves that there are risks of alloimmunization to these patients; hence the necessity to transfuse according to the protocol phenotyped and compatibility.},
 year = {2015}
}

Copy | Download

TY - JOUR
T1 - Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire
AU - Sekongo Yassongui Mamadou
AU - Kouamenan Goore Sidonie
AU - Kassogue Kadidia
AU - Konan Sidoine
AU - Kouassi Parfait
AU - Lagou Amélie Delphine
AU - Kouacou-Ama Patricia
AU - Konate Seidou
AU - Abisse Agba
Y1 - 2015/07/04
PY - 2015
N1 - https://doi.org/10.11648/j.iji.20150304.11
DO - 10.11648/j.iji.20150304.11
T2 - International Journal of Immunology
JF - International Journal of Immunology
JO - International Journal of Immunology
SP - 47
EP - 51
PB - Science Publishing Group
SN - 2329-1753
UR - https://doi.org/10.11648/j.iji.20150304.11
AB - The objective of this study is to establish the mapping of blood group and phenotype Rhesus and Kell and compare it to the population of blood donors. Methodology: It is a prospective study performed in transfusion therapy unit (UTT) of the national blood transfusion center (NBTC) of Abidjan on sickle cell desease patients multitransfused between February and October 2013. The blood group ABO and phenotype Rhesus and Kell of the patients was performed by the gel agglutination technique. The statistical analysis was performed using SPSS 15.0 software. Results: Among the 145 patients followed by the UTT, males predominated with (sex ratio 1.27). The median age was 14 years. Homozygous sickle cell disease (SS) was more frequent (57.25%). The blood group O was more represented (54.6%). Ag D was found in 96%. The Ag C (16.5%) and Ag E (14.5%) have lower frequencies than those founded in the population of blood donors (Ag C 21.6% and Ag E 22.2%). The most phenotype rhesus and kell frequently encountered to the patients was C- c+ E- e+ K- (49.7%). These frequencies are lower than those of the blood donors population. Conclusion: Blood group O is the most common to our patients. The Ag D is the most found. The phenotype Rhesus and kell C- c + D + E- e- K- predominates with but remains below the frequencies reported among blood donors. This proves that there are risks of alloimmunization to these patients; hence the necessity to transfuse according to the protocol phenotyped and compatibility.
VL - 3
IS - 4
ER -

Copy | Download

Author Information

Sekongo Yassongui Mamadou

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire
Kouamenan Goore Sidonie

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire
Kassogue Kadidia

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire
Konan Sidoine

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire
Kouassi Parfait

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire
Lagou Amélie Delphine

Nephrology service, University Hospital of Yopougon, Abidjan, C?te d’Ivoire
Kouacou-Ama Patricia

Immunology service, University Hospital of Cocody, Abidjan, C?te d’Ivoire
Konate Seidou

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire
Abisse Agba

Therapeutic and Research Unit, National Blood Transfusion Center, Abidjan, C?te d’Ivoire

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Sekongo Yassongui Mamadou, Kouamenan Goore Sidonie, Kassogue Kadidia, Konan Sidoine, Kouassi Parfait, et al. (2015). Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire. International Journal of Immunology, 3(4), 47-51. https://doi.org/10.11648/j.iji.20150304.11

Copy | Download

ACS Style

Sekongo Yassongui Mamadou; Kouamenan Goore Sidonie; Kassogue Kadidia; Konan Sidoine; Kouassi Parfait, et al. Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire. Int. J. Immunol. 2015, 3(4), 47-51. doi: 10.11648/j.iji.20150304.11

Copy | Download

AMA Style

Sekongo Yassongui Mamadou, Kouamenan Goore Sidonie, Kassogue Kadidia, Konan Sidoine, Kouassi Parfait, et al. Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire. Int J Immunol. 2015;3(4):47-51. doi: 10.11648/j.iji.20150304.11

Copy | Download

@article{10.11648/j.iji.20150304.11,
  author = {Sekongo Yassongui Mamadou and Kouamenan Goore Sidonie and Kassogue Kadidia and Konan Sidoine and Kouassi Parfait and Lagou Amélie Delphine and Kouacou-Ama Patricia and Konate Seidou and Abisse Agba},
  title = {Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire},
  journal = {International Journal of Immunology},
  volume = {3},
  number = {4},
  pages = {47-51},
  doi = {10.11648/j.iji.20150304.11},
  url = {https://doi.org/10.11648/j.iji.20150304.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150304.11},
  abstract = {The objective of this study is to establish the mapping of blood group and phenotype Rhesus and Kell and compare it to the population of blood donors. Methodology: It is a prospective study performed in transfusion therapy unit (UTT) of the national blood transfusion center (NBTC) of Abidjan on sickle cell desease patients multitransfused between February and October 2013. The blood group ABO and phenotype Rhesus and Kell of the patients was performed by the gel agglutination technique. The statistical analysis was performed using SPSS 15.0 software. Results: Among the 145 patients followed by the UTT, males predominated with (sex ratio 1.27). The median age was 14 years. Homozygous sickle cell disease (SS) was more frequent (57.25%). The blood group O was more represented (54.6%). Ag D was found in 96%. The Ag C (16.5%) and Ag E (14.5%) have lower frequencies than those founded in the population of blood donors (Ag C 21.6% and Ag E 22.2%). The most phenotype rhesus and kell frequently encountered to the patients was C- c+ E- e+ K- (49.7%). These frequencies are lower than those of the blood donors population. Conclusion: Blood group O is the most common to our patients. The Ag D is the most found. The phenotype Rhesus and kell C- c + D + E- e- K- predominates with but remains below the frequencies reported among blood donors. This proves that there are risks of alloimmunization to these patients; hence the necessity to transfuse according to the protocol phenotyped and compatibility.},
 year = {2015}
}

Copy | Download